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1

Geschichte der Glucocorticoide: Ein kurzer Abriss

Heiko Mühl, Josef Pfeilschifter

Journal:

Pharmazie in unserer Zeit

Année:

2003

Langue:

german

Fichier:

PDF, 370 KB

german, 2003

2

Expression and release of chemokines associated with apoptotic cell death in human promonocytic U937 cells and peripheral blood mononuclear cells

Heiko Mühl, Marcel Nold, Jae-Hyung Chang, Stefan Frank, Wolfgang Eberhardt, Josef Pfeilschifter

Journal:

European Journal of Immunology

Année:

1999

Langue:

english

Fichier:

PDF, 304 KB

english, 1999

3

Molecular mechanisms of nitric oxide-dependent inhibition of TPA-induced matrix metalloproteinase-9 (MMP-9) in MCF-7 cells

Christine Jespersen, Anke Doller, El-Sayed Akool, Malte Bachmann, Roswitha Müller, Paul Gutwein, Heiko Mühl, Josef Pfeilschifter, Wolfgang Eberhardt

Journal:

Journal of Cellular Physiology

Année:

2009

Langue:

english

Fichier:

PDF, 379 KB

english, 2009

4

THERAPEUTIC STRATEGIES FOR THE INHIBITION OF INDUCIBLE NITRIC OXIDE SYNTHASE—POTENTIAL FOR A NOVEL CLASS OF ANTI-INFLAMMATORY AGENTS

JOSEF PFEILSCHIFTER, WOLFGANG EBERHARDT, RICHARD HUMMEL, DIETER KUNZ, HEIKO MÜHL, DOROTHEA NITSCH, CHRISTOPH PLÜSS, GABY WALKER

Journal:

Cell Biology International

Année:

1996

Langue:

english

Fichier:

PDF, 215 KB

english, 1996

5

Targeting caspase-1 by inhalation-therapy: effects of Ac-YVAD-CHO on IL-1β, IL-18 and downstream proinflammatory parameters as detected in rat endotoxaemia

Kim A. Boost, Sandra Hoegl, Christian Hofstetter, Michael Flondor, Klaus Stegewerth, Ilka Platacis, Josef Pfeilschifter, Heiko Muhl, Bernhard Zwissler

Journal:

Intensive Care Medicine

Année:

2007

Langue:

english

Fichier:

PDF, 290 KB

english, 2007

6

Effects of intravenous and inhaled levosimendan in severe rodent sepsis

Patrick Scheiermann, Devan Ahluwalia, Sandra Hoegl, Andrea Dolfen, Marc Revermann, Bernhard Zwissler, Heiko Muhl, Kim A. Boost, Christian Hofstetter

Journal:

Intensive Care Medicine

Année:

2009

Langue:

english

Fichier:

PDF, 225 KB

english, 2009

7

IL-18 initiates release of matrix metalloproteinase-9 from peripheral blood mononuclear cells without affecting tissue inhibitor of matrix metalloproteinases-1: suppression by TNFα blockage and modulation by IL-10

Marcel Nold, Andreas Goede, Wolfgang Eberhardt, Josef Pfeilschifter, Heiko Mühl

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 358 KB

english, 2003

8

Interleukin-18 secretion and Th1-like cytokine responses in human peripheral blood mononuclear cells under the influence of the toll-like receptor-5 ligand flagellin

Malte Bachmann, Katharina Horn, Marco A. Poleganov, Jens Paulukat, Marcel Nold, Josef Pfeilschifter, Heiko Mühl

Journal:

Cellular Microbiology

Année:

2006

Langue:

english

Fichier:

PDF, 338 KB

english, 2006

9

Inducible NO synthase and antibacterial host defence in times of Th17/Th22/T22 immunity

Heiko Mühl, Malte Bachmann, Josef Pfeilschifter

Journal:

Cellular Microbiology

Année:

2011

Langue:

english

Fichier:

PDF, 370 KB

english, 2011

10

Tetrahydrobiopterin is a limiting factor of nitric oxide generation in interleukin 1β-stimulated rat glomerular mesangial cells

Mühl, Heiko, Pfeilschifter, Josef

Journal:

Kidney International

Année:

1994

Langue:

english

Fichier:

PDF, 538 KB

english, 1994

11

The HIV protease inhibitor ritonavir synergizes with butyrate for induction of apoptotic cell death and mediates expression of heme oxygenase-1 in DLD-1 colon carcinoma cells

Heiko Mühl, Jens Paulukat, Sonja Höfler, Markus Hellmuth, Rochus Franzen, Josef Pfeilschifter

Journal:

British Journal of Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 319 KB

english, 2004

12

Systemic Anti-TNFα Treatment Restores Diabetes-Impaired Skin Repair in ob/ob Mice by Inactivation of Macrophages

Goren, Itamar, Müller, Elke, Schiefelbein, Dana, Christen, Urs, Pfeilschifter, Josef, Mühl, Heiko, Frank, Stefan

Journal:

The Journal of Investigative Dermatology

Année:

2007

Langue:

english

Fichier:

PDF, 376 KB

english, 2007

13

Cytokine production by leukocytes of Papillon–Lefèvre syndrome patients in whole blood cultures

Christian D. Sadik, Barbara Noack, Beate Schacher, Josef Pfeilschifter, Heiko Mühl, Peter Eickholz

Journal:

Clinical Oral Investigations

Année:

2012

Langue:

english

Fichier:

PDF, 141 KB

english, 2012

14

Inhibition of lipopolysaccharide/ATP-induced release of interleukin-18 by KN-62 and glyburide

Heiko Mühl, Sonja Höfler, Josef Pfeilschifter

Journal:

European Journal of Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 160 KB

english, 2003

15

Interleukin-18 bioactivity: a novel target for immunopharmacological anti-inflammatory intervention

Heiko Mühl, Josef Pfeilschifter

Journal:

European Journal of Pharmacology

Année:

2004

Langue:

english

Fichier:

PDF, 246 KB

english, 2004

16

Effects of high glucose on cytokine-induced nerve growth factor (NGF) expression in rat renal mesangial cells

Klaus Heese, Karl-Friedrich Beck, Meik Helmut Behrens, Katharina Plüss, Wolfgang Fierlbeck, Andrea Huwiler, Heiko Mühl, Helmut Geiger, Uwe Otten, Josef Pfeilschifter

Journal:

Biochemical Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 459 KB

english, 2003

17

IL-18BPa:Fc cooperates with immunosuppressive drugs in human whole blood

Marcel Nold, Ingeborg A. Hauser, Sonja Höfler, Andreas Goede, Wolfgang Eberhardt, Till Ditting, Helmut Geiger, Josef Pfeilschifter, Heiko Mühl

Journal:

Biochemical Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 233 KB

english, 2003

18

Immunopharmacology: anti-inflammatory therapy targeting transcription factors

Josef Pfeilschifter, Heiko Mühl

Journal:

European Journal of Pharmacology

Année:

1999

Langue:

english

Fichier:

PDF, 101 KB

english, 1999

19

Nitric oxide augments release of chemokines from monocytic U937 cells: modulation by anti-inflammatory pathways

Heiko Mühl, Jae-Hyung Chang, Andrea Huwiler, Markus Bosmann, Jens Paulukat, Rajko Ninic, Marcel Nold, Markus Hellmuth, Josef Pfeilschifter

Journal:

Free Radical Biology and Medicine

Année:

2000

Langue:

english

Fichier:

PDF, 294 KB

english, 2000

20

Molecular mechanisms of IL-18BP regulation in DLD-1 cells: pivotal direct action of the STAT1/GAS axis on the promoter level

Malte Bachmann, Jens Paulukat, Josef Pfeilschifter, Heiko Mühl

Journal:

Journal of Cellular and Molecular Medicine

Année:

2009

Langue:

english

Fichier:

PDF, 698 KB

english, 2009

21

IFN-gamma Impairs Release of IL-8 by IL-1beta-stimulated A549 Lung Carcinoma Cells

Kim A Boost, Christian D Sadik, Malte Bachmann, Bernhard Zwissler, Josef Pfeilschifter, Heiko Mühl

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 476 KB

english, 2008

22

Pharmacokinetics of Levofloxacin During Continuous Venovenous Hemodiafiltration and Continuous Venovenous Hemofiltration in Critically Ill Patients

Mr. Sven G. Guenter, Dr. Heiko Iven, Dr. Carsten Boos, Dr. Hans-Peter Bruch, Dr. Elke Muhl

Journal:

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy

Année:

2002

Langue:

english

Fichier:

PDF, 60 KB

english, 2002

23

Measurement and Calculation of the Extracorporeal Elimination of Vancomycin During Continuous Venovenous Hemodiafiltration and Continuous Venovenous Hemofiltration in Critically Ill Patients

Elke Muhl, Jens Bundesen, Heiko Iven, Hans-Peter Bruch

Journal:

Journal of Intensive Care Medicine

Année:

2001

Langue:

english

Fichier:

PDF, 129 KB

english, 2001

24

Interferon-γ Mediates Gene Expression of IL-18 Binding Protein in Nonleukocytic Cells

Heiko Mühl, Heiko Kämpfer, Markus Bosmann, Stefan Frank, Heinfried Radeke, Josef Pfeilschifter

Journal:

Biochemical and Biophysical Research Communications

Année:

2000

Langue:

english

Fichier:

PDF, 158 KB

english, 2000

25

Interleukin 1 and tumor necrosis factor potentiate angiotensin II- and calcium ionophore-stimulated prostaglandin E2 synthesis in rat renal mesangial cells

Josef Pfeilschifter, Heiko Mühl

Journal:

Biochemical and Biophysical Research Communications

Année:

1990

Langue:

english

Fichier:

PDF, 605 KB

english, 1990

26

Cyclosporin derivatives inhibit interleukin 1β induction of nitric oxide synthase in renal mesangial cells

Heiko Mühl, Dieter Kunz, Peter Rob, Josef Pfeilschifter

Journal:

European Journal of Pharmacology

Année:

1993

Langue:

english

Fichier:

PDF, 567 KB

english, 1993

27

PDGF suppresses the activation of group II phospholipase A2 gene expression by interleukin I and forskolin in mesangial cells

Heiko Mühl, Thomas Geiger, Werner Pignat, Fritz Märki, Henk van den Bosch, Klaus Vosbeck, Josef Pfeilschifter

Journal:

Année:

1991

Langue:

english

Fichier:

PDF, 530 KB

english, 1991

28

Transforming growth factors type-β and dexamethasone attenuate group II phospholipase A2 gene expression by interleukin-1 and forskolin in rat mesangial cells

Heiko Mühl, Thomas Geiger, Werner Pignat, Fritz Märki, Henk van den Bosch, Nico Cerletti, David Cox, Garry McMaster, Klaus Vosbeck, Josef Pfeilschifter

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 586 KB

english, 1992

29

Apoptosis is triggered by the cyclic AMP signalling pathway in renal mesangial cells

Heiko Mühl, Dorothea Nitsch, Katrin Sandau, Bernhard Brüne, Zoltan Varga, Josef Pfeilschifter

Journal:

Année:

1996

Langue:

english

Fichier:

PDF, 389 KB

english, 1996

30

Endothelial nitric oxide synthase: a determinant of TNFα production by human monocytes/macrophages

Heiko Mühl, Josef Pfeilschifter

Journal:

Biochemical and Biophysical Research Communications

Année:

2003

Langue:

english

Fichier:

PDF, 98 KB

english, 2003

31

The dsRNA-mimetic poly (I:C) and IL-18 synergize for IFNγ and TNFα expression

Amany Balah, El-Sayed Akool, Malte Bachmann, Josef Pfeilschifter, Heiko Mühl

Journal:

Biochemical and Biophysical Research Communications

Année:

2009

Langue:

english

Fichier:

PDF, 479 KB

english, 2009

32

Systematic analysis highlights the key role of TLR2/NF-κB/MAP kinase signaling for IL-8 induction by macrophage-like THP-1 cells under influence of Borrelia burgdorferi lysates

Christian D. Sadik, Klaus-Peter Hunfeld, Malte Bachmann, Peter Kraiczy, Wolfgang Eberhardt, Volker Brade, Josef Pfeilschifter, Heiko Mühl

Journal:

The International Journal of Biochemistry & Cell Biology

Année:

2008

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2008

33

Immunomodulation via TLR3/IRF3 by misplaced U1-snRNA as detected in human A549 lung epithelial cells

Christan D. Sadik, Malte Bachmann, Josef Pfeilschifter, Heiko Mühl

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 48 KB

english, 2009

34

A brief exposure to isoflurane (50 s) significantly impacts on plasma cytokine levels in endotoxemic rats

Christian Hofstetter, Michael Flondor, Kim A. Boost, Patricia Koehler, Markus Bosmann, Josef Pfeilschifter, Bernhard Zwissler, Heiko Mühl

Journal:

International Immunopharmacology

Année:

2005

Langue:

english

Fichier:

PDF, 144 KB

english, 2005

35

Comparing hemodynamics, blood gas analyses and proinflammatory cytokines in endotoxemic and severely septic rats

Patrick Scheiermann, Sandra Hoegl, Christian Hofstetter, Josef Pfeilschifter, Bernhard Zwissler, Heiko Mühl, Kim A. Boost, Bertram Scheller

Journal:

International Immunopharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 249 KB

english, 2011

36

Cecal Ligation and Incision: An Acute Onset Model of Severe Sepsis in Rats

Patrick Scheiermann, Sandra Hoegl, Marc Revermann, Devan Ahluwalia, Johannes Zander, Kim A. Boost, Thach Nguyen, Bernhard Zwissler, Heiko Muhl, Christian Hofstetter

Journal:

Journal of Surgical Research

Année:

2009

Langue:

english

Fichier:

PDF, 451 KB

english, 2009

37

Genome-wide analysis displays marked induction of EBI3/IL-27B in IL-18-activated AML-derived KG1 cells: Critical role of two κB binding sites in the human EBI3 promotor

Marco A. Poleganov, Malte Bachmann, Josef Pfeilschifter, Heiko Mühl

Journal:

Molecular Immunology

Année:

2008

Langue:

english

Fichier:

PDF, 974 KB

english, 2008

38

Inhaled IL-10 reduces biotrauma and mortality in a model of ventilator-induced lung injury

Sandra Hoegl, Kim A. Boost, Holger Czerwonka, Andrea Dolfen, Patrick Scheiermann, Heiko Muhl, Bernhard Zwissler, Christian Hofstetter

Journal:

Respiratory Medicine

Année:

2009

Langue:

english

Fichier:

PDF, 381 KB

english, 2009

39

Nitric oxide donors induce apoptosis in glomerular mesangial cells, epithelial cells and endothelial cells

Heiko Mühl, Katrin Sandau, Bernhard Brüne, Vreny A. Briner, Josef Pfeilschifter

Journal:

European Journal of Pharmacology

Année:

1996

Langue:

english

Fichier:

PDF, 1.03 MB

english, 1996

40

Nitric oxide differentially regulates pro- and anti-angiogenic markers in DLD-1 colon carcinoma cells

Markus Hellmuth, Jens Paulukat, Raiko Ninic, Josef Pfeilschifter, Heiko Mühl

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 219 KB

english, 2004

41

Anti-inflammatory properties of pro-inflammatory interferon-γ

Heiko Mühl, Josef Pfeilschifter

Journal:

International Immunopharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 243 KB

english, 2003

42

Expression of nitric oxide synthase in rat glomerular mesangial cells mediated by cyclic AMP

Heiko Mühl, Dieter Kunz, Josef Pfeilschifter

Journal:

British Journal of Pharmacology

Année:

1994

Langue:

english

Fichier:

PDF, 1.83 MB

english, 1994

43

IFNα converts IL-22 into a cytokine efficiently activating STAT1 and its downstream targets

Bachmann, Malte, Ulziibat, Solongo, Härdle, Lorena, Pfeilschifter, Josef, Mühl, Heiko

Journal:

Biochemical Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 297 KB

english, 2013

44

Interleukin-22 predicts severity and death in advanced liver cirrhosis: a prospective cohort study

Bernd Kronenberger, Ina Rudloff, Malte Bachmann, Friederike Brunner, Lisa Kapper, Natalie Filmann, Oliver Waidmann, Eva Herrmann, Josef Pfeilschifter, Stefan Zeuzem, Albrecht Piiper, Heiko Mühl

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 647 KB

english, 2012

45

Application of Interleukin-22 Mediates Protection in Experimental Acetaminophen-Induced Acute Liver Injury

Scheiermann, Patrick, Bachmann, Malte, Goren, Itamar, Zwissler, Bernhard, Pfeilschifter, Josef, Mühl, Heiko

Journal:

The American Journal of Pathology

Année:

2013

Langue:

english

Fichier:

PDF, 786 KB

english, 2013

46

IL-22 in tissue-protective therapy

Mühl, Heiko, Scheiermann, Patrick, Bachmann, Malte, Härdle, Lorena, Heinrichs, Anika, Pfeilschifter, Josef

Journal:

British Journal of Pharmacology

Année:

2013

Langue:

english

Fichier:

PDF, 719 KB

english, 2013

47

Interleukin-22 serum levels are a negative prognostic indicator in patients with hepatocellular carcinoma

Waidmann, Oliver, Kronenberger, Bernd, Scheiermann, Patrick, Köberle, Verena, Mühl, Heiko, Piiper, Albrecht

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 688 KB

english, 2014

48

Molecular mechanisms of PDGF-AA expression induced by the dsRNA-mimetic poly (I:C) and IL-18

Balah, Amany, Mühl, Heiko, Pfeilschifter, Josef, Akool, El-Sayed

Journal:

Biochemical and Biophysical Research Communications

Année:

2013

Langue:

english

Fichier:

PDF, 818 KB

english, 2013

49

Expanding Extracellular Zinc Beyond Levels Reflecting the Albumin-Bound Plasma Zinc Pool Potentiates the Capability of IL-1 β , IL-18, and IL-12 to Act as IFN- γ -Inducing Factors on PBMC

Poleganov, Marco A., Pfeilschifter, Josef, Mühl, Heiko

Journal:

Journal of Interferon & Cytokine Research

Année:

2007

Langue:

english

Fichier:

PDF, 180 KB

english, 2007

50

Two Distinct Signaling Pathways Trigger the Expression of Inducible Nitric Oxide Synthase in Rat Renal Mesangial Cells

Dieter Kunz, Heiko Muhl, Gaby Walker and Josef Pfeilschifter

Journal:

Proceedings of the National Academy of Sciences

Année:

1994

Langue:

english

Fichier:

PDF, 1.26 MB

english, 1994